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King Fahad Medical City (KFMC) Launches (EPIC) Project for Patient Services 17 Projects Win Awards for Implementation of Quality Projects in Patients Services for 2019 …
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Simvastatin needs to be activated by NaOH in EtOH treatment before use for cell assay. Simvastatin suppresses cholesterol synthesis in mouse L-M cell, rat H4II E cell, and human Hep G2 cell with IC 50 s of 19.3 nM, 13.3 nM and 15.6 nM, respectively.Simvastatin causes a dose-dependent increase in serine 473 phosphorylation of Akt within 30 minutes, with maximal phosphorylation occurring at 1.0 µM.
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