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Cannabinoids as therapeutic for PTSD - ScienceDirect While the first two randomized controlled trials of cannabinoids (i.e. THC, CBD, and THC + CBD) for PTSD are currently underway (see NCT02759185 and NCT02517424), published research examining the impact of cannabinoids on PTSD remains in its infancy. Based on the early stage of this research, one must consider a number of methodological